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. 2013 May-Jun;110(3):207-11.

The Mighty Mouse: the impact of rodents on advances in biomedical research

Affiliations

The Mighty Mouse: the impact of rodents on advances in biomedical research

Elizabeth C Bryda. Mo Med. 2013 May-Jun.

Abstract

Mice and rats have long served as the preferred species for biomedical research animal models due to their anatomical, physiological, and genetic similarity to humans. Advantages of rodents include their small size, ease of maintenance, short life cycle, and abundant genetic resources. The Rat Resource and Research Center (RRRC) and the MU Mutant Mouse Regional Resource Center (MMRRC) serve as centralized repositories for the preservation and distribution of the ever increasing number of rodent models.

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Figures

Figure 1
Figure 1
Example of fluorescence seen in EGFP rat strains. Pictures of organs from SDTg(GFP)2BalRrrc (RRRC:0065) animals (images on right of each panel) and wild type controls (images on left of each panel). Upper images for each panel are under bright light, bottom images for each panel are under fluorescent light. Panel A: kidney; Panel B: eye; Panel C: lung; Panel D: heart.
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