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Case Reports
. 2012 Jul;3(2):187-9.
doi: 10.4103/0975-5950.111377.

Primary extra nodal non-Hodgkin's lymphoma of the oral cavity in a young girl

Ponnurangam N Vinoth  1 , Sathyamoorthi Muthamil Selvan, Latika Sahni, Kannan Krishnaratnam, Swaminathan Rajendiran, Chidambaram Vishwanath Anand, Julius X Scott
Affiliations
Case Reports

Primary extra nodal non-Hodgkin's lymphoma of the oral cavity in a young girl

Ponnurangam N Vinoth et al. Natl J Maxillofac Surg. 2012 Jul.

Abstract

Primary Non Hodgkin s Lymphoma (NHL) usually arises within the lymphnodes, but 20-30% account for extra nodal sites. Oral cavity, as a primary extra nodal site for NHL, is relatively rare and diverse in presentation, response to therapy and prognosis. We report a 14 year old adolescent girl who presented with multiple gingival swellings, the most prominent one being in the right anterior maxilla. Gingival biopsy showed NHL- diffuse large B cell type. Child was completely cured with chemotherapy and now she is in complete remission and under regular follow up.

Keywords: Extra nodal; NHL; gingival; oral cavity.

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Conflict of interest statement

Conflict of Interest: None declared

Figures

Figure 1
Figure 1
Gingival swelling
Figure 2
Figure 2
Sheets of atypical lymphoid cells with hyperchromatic nuclei and scant cytoplasm (H and E, × 400). The upper insert shows increased number of CD 20 positive cells (IHC × 100). Only a few scattered cells in the background are positive for CD 3 in the lower insert (IHC × 100). This staining pattern is diagnostic of NHL – Diffuse large B-cell type
Figure 3
Figure 3
CT scan – Paranasal sinuses: a large homogenous soft tissue lesion in the left masticator space with erosion of the postero lateral wall of left maxillary sinus and extension of the mass lesion into the left maxillary sinus
See this image and copyright information in PMC

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References

    1. Clark RM, Fitzpatrick PJ, Gospodarowitcz MK. Extranodal malignant lymphomas of the head and neck. J Otolaryngol. 1983;12:239–45. - PubMed
    1. Spatafore CM, Keyes G, Skidmore AE. Lymphoma: An unusual presentation. J Endod. 1989;15:438–41. - PubMed
    1. Ratech H, Burke JS, Blayney DW, Sheibani K, Rappaport H. A clinicopathologic study of malignant lymphomas of the nose, paranasal sinuses, and hard palate, including cases of lethal midline granuloma. Cancer. 1989;64:2525–31. - PubMed
    1. Wong DS, Fuller LM, Butler JJ, Shullenberg CC. Extranodal non-Hodgkin's lymphomas of the head and neck. Am J Roetgenol Radium Ther Nucl Med. 1975;123:471–81. - PubMed
    1. Griffin TJ, Hurst PS, Swanson J. Non Hodgkin's lymphoma: Case involving four third molar extraction sites. Oral Surg Oral Med Oral Pathol. 1988;65:671–4. - PubMed

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