Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2013 Jul 8;14(4):4087.
doi: 10.1120/jacmp.v14i4.4087.

Deep inspiration breath-hold technique guided by an opto- electronic system for extracranial stereotactic treatments

Affiliations

Deep inspiration breath-hold technique guided by an opto- electronic system for extracranial stereotactic treatments

Cristina Garibaldi et al. J Appl Clin Med Phys. .

Abstract

The purpose of this work was to evaluate the intrapatient tumor position reproducibility in a deep inspiration breath-hold (DIBH) technique based on two infrared optical tracking systems, ExacTrac and ELITETM, in stereotactic treatment of lung and liver lesions. After a feasibility study, the technique was applied to 15 patients. Each patient, provided with a real-time visual feedback of external optical marker displacements, underwent a full DIBH, a free-breathing (FB), and three consecutive DIBH CT-scans centered on the lesion to evaluate the tumor position reproducibility. The mean reproducibility of tumor position during repeated DIBH was 0.5 ± 0.3 mm in laterolateral (LL), 1.0 ± 0.9 mm in anteroposterior (AP), and 1.4 ± 0.9 mm in craniocaudal (CC) direction for lung lesions, and 1.0 ± 0.6 mm in LL, 1.1 ± 0.5 mm in AP, and 1.2 ± 0.4 mm in CC direction for liver lesions. Intra- and interbreath-hold reproducibility during treatment, as determined by optical markers displacements, was below 1 mm and 3 mm, respectively, in all directions for all patients. Optically-guided DIBH technique provides a simple noninvasive method to minimize breathing motion for collaborative patients. For each patient, it is important to ensure that the tumor position is reproducible with respect to the external markers configuration.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Patient with passive markers and eyewear viewer (a) showing in real‐time marker displacements in LL, CC, and AP directions (with respect to a reference configuration (b)).
Figure 2
Figure 2
Reproducibility of tumor position during repeated DIBH CT scans fused on the FB CT scan (shown in pink).
Figure 3
Figure 3
Displacement of GTV and passive markers between FB and DIBH in all directions for lung lesions.
Figure 4
Figure 4
Displacement of GTV and passive markers between FB and DIBH in all directions for liver lesions.

References

    1. van Herk M. Errors and margins in radiotherapy. Semin Radiat Oncol. 2004;14(1):52–64. - PubMed
    1. Chen GTY, Kung JH, Beaudette KP. Artifacts in computed tomography scanning of moving objects. Semin Radiat Oncol. 2004;14(1):19–26. - PubMed
    1. Murray B, Forster K, Timmerman R. Frame‐based immobilization and targeting for stereotactic body irradiation therapy. Med Dosim. 2007;32(2):86–91. - PubMed
    1. Kubo HD and Hill BC. Respiration gated radiotherapy treatment: a technical study. Phys Med Biol. 1996;41(1):83–91. - PubMed
    1. Zhang T, Keller H, O'Brien MJ, Mackie TR, Paliwal B. Application of the spirometer in respiratory gated radiotherapy. Med Phys. 2003;30(12):3165–71. - PubMed

MeSH terms