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Review
. 2013 Oct;10(10):585-95.
doi: 10.1038/nrgastro.2013.117. Epub 2013 Jul 9.

Extraintestinal manifestations and complications in IBD

Affiliations
Review

Extraintestinal manifestations and complications in IBD

Claudia Ott et al. Nat Rev Gastroenterol Hepatol. 2013 Oct.

Abstract

More than one-third of patients with IBD are affected by extraintestinal manifestations or extraintestinal complications beyond the intestinal manifestation of the disease. The most common manifestations include arthropathies, mucocutaneous and ophthalmological manifestations, as well as conditions affecting the hepatobiliary system, both in Crohn's disease and ulcerative colitis. However, less frequent manifestations, such as pulmonary or neurological manifestations, should also be considered in patients with IBD. Several extraintestinal manifestations follow the course of the underlying intestinal activity, whereas others are independent from the intestinal inflammation. Extraintestinal complications such as iron-deficiency anaemia and osteoporosis are consequences of the intestinal disease or of disease-specific treatment. As extraintestinal manifestations and complications strongly influence quality of life, and to avoid severe complications, adequate treatment is mandatory in affected patients. We provide a comprehensive overview of different extraintestinal manifestations and complications, including their management, in patients with IBD.

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References

    1. Nat Clin Pract Gastroenterol Hepatol. 2005 Jun;2(6):266-72 - PubMed
    1. Inflamm Bowel Dis. 2005 Jan;11(1):62-72 - PubMed
    1. N Engl J Med. 1998 Jul 30;339(5):292-9 - PubMed
    1. Am J Surg. 1983 Jan;145(1):106-12 - PubMed
    1. Rheumatology (Oxford). 2001 Nov;40(11):1256-61 - PubMed

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