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. 2012 Sep 26;1(9):e8.
doi: 10.1038/psp.2012.8.

CPT: Pharmacometrics and Systems Pharmacology

Affiliations

CPT: Pharmacometrics and Systems Pharmacology

Piet H van der Graaf. CPT Pharmacometrics Syst Pharmacol. .

Abstract

Welcome to the first issue of CPT: Pharmacometrics and Systems Pharmacology (CPT:PSP), a new journal from the American Society for Clinical Pharmacology and Therapeutics. CPT:PSP is a cross-disciplinary journal devoted to publishing advances in quantitative, model-based approaches as applied in pharmacology, (patho)physiology, and disease to aid the discovery, development, and utilization of human therapeutics. The emphasis of CPT:PSP will be on the application of modeling and simulation and the impact of Pharmacometrics and Systems Pharmacology on the discovery and development of innovative therapies.CPT: Pharmacometrics & Systems Pharmacology (2012) 1, e8; doi:10.1038/psp.2012.8; advance online publication 26 September 2012.

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Figures

Figure 1
Figure 1
An integrated view of model-based drug discovery and development. CPT: Pharmacometrics and Systems Pharmacology (CPT:PSP) welcomes contributions of research across the whole spectrum of Pharmacometrics and Systems Pharmacology, with emphasis on application and impact on innovation of therapeutics. The common focus will be on quantitative methods that improve our understanding of pharmacology and therapeutics in humans. This is based on Figure 3 in the work of van der Graaf and Benson, which was further developed with input from Peter Milligan (Pfizer) and redrawn with permission from Pharmaceutical Research. PD, pharmacodynamics; PK, pharmacokinetics; PKPD, pharmacokinetics–pharmacodynamics.

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