Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2013 Jun;19(2):190-4.
doi: 10.3350/cmh.2013.19.2.190.

Pseudocirrhosis as a complication after chemotherapy for hepatic metastasis from breast cancer

Woo Kyoung Jeong  1 , Seo-Youn Choi, Jinoo Kim
Affiliations
Case Reports

Pseudocirrhosis as a complication after chemotherapy for hepatic metastasis from breast cancer

Woo Kyoung Jeong et al. Clin Mol Hepatol. 2013 Jun.
No abstract available

Keywords: Breast cancer; Chemotherapy; Metastasis; Nodular regenerative hyperplasia; Pseudocirrhosis.

PubMed Disclaimer

Conflict of interest statement

The authors have no conflicts to disclose.

Figures

Figure 1
Figure 1
A 53-year-old woman with hepatic metastasis from right breast cancer. (A) An initial CT scan shows multiple metastatic nodules in the whole liver (arrows). Hepatomegaly is also noted, and the parenchymal attenuation is somewhat decreased. Small thrombus (open arrow) in the right portal vein is seen. (B) One and half month later, follow-up CT scan shows that metastatic nodules are coalesced and less prominent (arrows). The volume of liver is decreased, and capsular retraction is more prominent. The thrombus in the portal vein disappears. (C) Seven months later, the last follow-up CT scan shows that the volume loss and capsular retraction of the liver is more and more prominent. Ascitic fluid around perihepatic space and splenomegaly are newly developed, and suggests the signs of portal hypertension.
Figure 2
Figure 2
A 25-year-old woman with multiple hepatic metastases from left breast cancer. (A) On the initial CT scan, numerous metastases (arrows) scattered in the whole liver are noted, and neither decreased volume nor capsular retraction of the liver is seen. (B) Two months later, the metastases are decreased and coalesced (arrows). The liver volume is increased, and the contour of the liver becomes lobulated. The parenchymal attenuation is decreased due to fatty change. (C) On 5 months from the initial CT, the follow-up CT shows geographic lesions around coalesced metastatic lesions are developed. Decreased hepatic volume and capsular retraction are noted. (D) On the last follow-up after 9 months, the shrinkage of the liver is more prominent and perihepatic ascites is developed.
See this image and copyright information in PMC

References

    1. Jha P, Poder L, Wang ZJ, Westphalen AC, Yeh BM, Coakley FV. Radiologic mimics of cirrhosis. AJR Am J Roentgenol. 2010;194:993–999. - PubMed
    1. Qayyum A, Lee GK, Yeh BM, Allen JN, Venook AP, Coakley FV. Frequency of hepatic contour abnormalities and signs of portal hypertension at CT in patients receiving chemotherapy for breast cancer metastatic to the liver. Clin Imaging. 2007;31:6–10. - PubMed
    1. Sonnenblick A, Appelbaum L, Peretz T. Liver failure on the background of pseudocirrhosis in patients with liver metastasis from breast cancer, who responded to treatment. Onkologie. 2011;34:199–201. - PubMed
    1. Kang SP, Taddei T, McLennan B, Lacy J. Pseudocirrhosis in a pancreatic cancer patient with liver metastases: a case report of complete resolution of pseudocirrhosis with an early recognition and management. World J Gastroenterol. 2008;14:1622–1624. - PMC - PubMed
    1. Young ST, Paulson EK, Washington K, Gulliver DJ, Vredenburgh JJ, Baker ME. CT of the liver in patients with metastatic breast carcinoma treated by chemotherapy: findings simulating cirrhosis. AJR Am J Roentgenol. 1994;163:1385–1388. - PubMed

Publication types

MeSH terms

LinkOut - more resources