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. 2013:2013:631825.
doi: 10.1155/2013/631825. Epub 2013 Jun 13.

Adult T-Cell Leukemia-Lymphoma during Pregnancy

Martin Miguel Amor  1 , Aedan Simon Olaso, Robert Atienza, Benjamin Stueben, Seth Cohen, Plamen Kossev
Affiliations

Adult T-Cell Leukemia-Lymphoma during Pregnancy

Martin Miguel Amor et al. Case Rep Oncol Med. 2013.

Abstract

Adult T-cell leukemia-lymphoma (ATL) is an uncommon highly aggressive T-cell lymphoma associated with human T-cell lymphotropic virus type 1 (HTLV-1) infection. It is rarely encountered during pregnancy and is particularly challenging to treat due to its aggressive nature and because of the lack of robust data on optimal chemotherapy. We report a case of a Jamaican immigrant diagnosed with ATL during pregnancy.

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Figures

Figure 1
Figure 1
Chest radiograph of patient showing diffuse lytic bone lesions (indicated by blue arrows), most prominent in bilateral humeri and healed fracture deformities in the clavicles and ribs.
Figure 2
Figure 2
Minute fragment of core biopsy with morphology consistent with an intermediate to large cell aggressive T-cell lymphoma. These neoplastic cells were strongly positive for CD25 supporting the diagnosis of ATL.
Figure 3
Figure 3
MRI of the brain revealed scattered subcortical T2-hyperintense foci and enhancing nodules in the calvarium (indicated by red arrows), consistent with metastatic disease.
See this image and copyright information in PMC

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