Biofilm-associated infections: antibiotic resistance and novel therapeutic strategies
- PMID: 23841634
- DOI: 10.2217/fmb.13.58
Biofilm-associated infections: antibiotic resistance and novel therapeutic strategies
Abstract
Infections with bacterial or fungal biofilms have emerged as a major public heath concern because biofilm-growing cells are highly resistant to both antibiotics and host immune defenses. This review focuses on the progress in understanding the mechanisms of biofilm-specific antimicrobial resistance and in developing innovative therapeutic measures based on novel antibiofilm agents.
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