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Comment
. 2013 Jul 23;110(30):12166-7.
doi: 10.1073/pnas.1310671110. Epub 2013 Jul 10.

Insight into the unknown marine virus majority

Alexander I Culley  1
Affiliations
Comment

Insight into the unknown marine virus majority

Alexander I Culley. Proc Natl Acad Sci U S A. .
No abstract available

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Conflict of interest statement

The author declares no conflict of interest.

Figures

Fig. 1.
Fig. 1.
A simplified depiction of how the addition of the SAR116 and SAR11 phages to the catalog of known viruses results in the identification of substantially more of the marine phage community. A seawater sample containing a community of viruses is harvested from the ocean, the viral genomes are extracted, and a metagenome is generated through random sequencing. To identify the viruses in the sample, the metagenomic sequences are compared with a reference library of known viruses. The identification of these viruses is ultimately dependent on their similarity to viruses in the reference database. The addition of the SAR phages results in the identification of ∼30% more metagenomic sequences (6). In the reference database, the orange, light green, and pink circles represent known, SAR116, and SAR11 phages, respectively. A question mark next to a row of sequences indicates the sequences remain unidentified, and an ID indicates the sequences are known. Graphics by Amanda Toperoff.
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References

    1. Spencer R. Indigenous marine bacteriophages. J Bacteriol. 1960;79(4):614. - PMC - PubMed
    1. Torrella F, Morita RY. Evidence by electron micrographs for a high incidence of bacteriophage particles in the waters of Yaquina Bay, Oregon: Ecological and taxonomical implications. Appl Environ Microbiol. 1979;37(4):774–778. - PMC - PubMed
    1. Bergh Ø, Børsheim KY, Bratbak G, Heldal M. High abundance of viruses found in aquatic environments. Nature. 1989;340(6233):467–468. - PubMed
    1. Proctor L, Fuhrman J. Viral mortality of marine bacteria and cyanobacteria. Nature. 1990;343(6253):60–62.
    1. Edwards RA, Rohwer F. Viral metagenomics. Nat Rev Microbiol. 2005;3(6):504–510. - PubMed

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