Guidelines for the Programmatic Management of Drug-Resistant Tuberculosis: 2011 Update
- PMID: 23844450
- Bookshelf ID: NBK148644
Guidelines for the Programmatic Management of Drug-Resistant Tuberculosis: 2011 Update
Excerpt
This 2011 update of Guidelines for the programmatic management of drug-resistant tuberculosis is intended as a tool for use by public health professionals working in response to the Sixty-second World Health Assembly's resolution on prevention and control of multidrug-resistant tuberculosis and extensively drug-resistant tuberculosis. Resolution WHA62.15, adopted in 2009, calls on Member States to develop a comprehensive framework for the management and care of patients with drug-resistant TB.
The recommendations contained in these guidelines address the most topical questions concerning the programmatic management of drug-resistant TB: case-finding, multidrug resistance, treatment regimens, monitoring the response to treatment, and selecting models of care. The guidelines primarily target staff and medical practitioners working in TB treatment and control, and partners and organizations providing technical and financial support for care of drug-resistant TB in settings where resources are limited.
Copyright © 2011, World Health Organization.
Sections
- Abbreviations
- Acknowledgements
- Executive summary
- Funding and declarations of interest
- Objectives of the guidelines and target audience
- Background and methods
- 1. Rapid drug susceptibility testing for early start of appropriate treatment
- 2. Monitoring the response to MDR-TB treatment
- 3. Composition of second-line anti-tuberculosis regimens
- 4. Duration of second-line anti-tuberculosis regimens
- 5. Use of antiretrovirals in patients on second-line anti-tuberculosis regimens
- 6. Models of care for managing MDR-TB
- Research gaps
- Annex 1 Methods for evidence reviews and modelling
- Annex 2 GRADE glossary and summary of evidence tables
- Annex 3 Potentially overlapping toxicities of antiretrovirals and anti-tuberculosis agents (including first-line anti-tuberculosis agents)
- References
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