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Comment
. 2013 Jul 8;23(13):R570-2.
doi: 10.1016/j.cub.2013.05.032.

Mitophagy: mitofusin recruits a mitochondrial killer

Leo Pallanck  1
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Mitophagy: mitofusin recruits a mitochondrial killer

Leo Pallanck. Curr Biol. .
Free article

Abstract

Parkin is a cytosolic ubiquitin ligase that translocates to damaged mitochondria and promotes their degradation. Recent work demonstrates that a phosphorylated form of the mitochondrial fusion protein Mitofusin 2 serves as a receptor for Parkin translocation to damaged mitochondria.

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