Azathioprine and allopurinol: a potentially dangerous combination
- PMID: 2384739
- DOI: 10.1111/j.1365-2796.1990.tb00195.x
Azathioprine and allopurinol: a potentially dangerous combination
Abstract
We report the association of leucopenia and anaemia in five patients given a combination of azathioprine and allopurinol. Three subjects were renal transplant recipients with mild to moderate impairment of graft function. The complication appeared between 4 and 6 weeks following initiation of the combination therapy. Discontinuation of one of the two drugs resulted in full recovery within 4-8 weeks.
Comment in
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Allopurinol-azathioprine interaction.J Intern Med. 1991 Apr;229(4):386. J Intern Med. 1991. PMID: 2026995 No abstract available.
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The interaction between allopurinol and azathioprine.J Intern Med. 1993 May;233(5):426-7. J Intern Med. 1993. PMID: 8487012 No abstract available.
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