Applying trial sequential analysis on a negative meta-analysis: where is the real benefit?

Comment

Georges Khoueiry et al. Heart Lung. 2013 Sep-Oct.

. 2013 Sep-Oct;42(5):392-3.

doi: 10.1016/j.hrtlng.2013.06.048. Epub 2013 Jul 12.

No abstract available

Comment on

Do omega-3 polyunsaturated fatty acids reduce risk of sudden cardiac death and ventricular arrhythmias? A meta-analysis of randomized trials.
Khoueiry G, Abi Rafeh N, Sullivan E, Saiful F, Jaffery Z, Kenigsberg DN, Krishnan SC, Khanal S, Bekheit S, Kowalski M. Khoueiry G, et al. Heart Lung. 2013 Jul-Aug;42(4):251-6. doi: 10.1016/j.hrtlng.2013.03.006. Epub 2013 May 25. Heart Lung. 2013. PMID: 23714269
Omega-3 polyunsaturated fatty acids for patients at risk of sudden cardiac death and ventricular arrhythmias: trial sequential analysis.
Messori A, Fadda V, Maratea D, Trippoli S. Messori A, et al. Heart Lung. 2013 Sep-Oct;42(5):391-2. doi: 10.1016/j.hrtlng.2013.06.002. Epub 2013 Jul 9. Heart Lung. 2013. PMID: 23849506 No abstract available.