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Case Reports
. 1990 Apr;66(774):310-1.
doi: 10.1136/pgmj.66.774.310.

Rifampicin-induced upper gastrointestinal bleeding

S A Zargar  1 , B R Thapa, A Sahni, S Mehta
Affiliations
Case Reports

Rifampicin-induced upper gastrointestinal bleeding

S A Zargar et al. Postgrad Med J. 1990 Apr.

Abstract

Gastrointestinal disturbances like anorexia, nausea, vomiting, abdominal discomfort and diarrhoea are known adverse effects of rifampicin. We report an upper gastrointestinal bleeding due to haemorrhagic gastric erosions after ingestion of rifampicin for pulmonary tuberculosis. The cause and effect relationship between development of haemorrhagic gastric erosions and rifampicin administration was confirmed by rechallenge with rifampicin. To our knowledge no such adverse effect of rifampicin has been reported previously.

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