Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2013:8:817-23.
doi: 10.2147/CIA.S45468. Epub 2013 Jul 3.

Short- and long-term mortality in males and females with fragility hip fracture in Norway. A population-based study

Andreas P Diamantopoulos  1 , Mari Hoff, Inger M Skoie, Marc Hochberg, Glenn Haugeberg
Affiliations

Short- and long-term mortality in males and females with fragility hip fracture in Norway. A population-based study

Andreas P Diamantopoulos et al. Clin Interv Aging. 2013.

Abstract

Background: Hip fracture patients have, in several studies, been shown to have excessive mortality. There is, however, a lack of mortality data, in comparison to incidence data, from the last decade in particular.

Objective: To study short- and long-term mortality in a population-based cohort of hip fracture patients over the last decade and compare it to the background population.

Patients and methods: Fragility hip fracture patients in the two most southern counties in Norway who experienced fractures in 2004 and 2005 were studied. For each patient, three controls were randomly recruited from the background population matched for age, sex, and residency. Overall, age-, gender-, and group-specific mortality rates were calculated.

Results: A total of 942 (267 male and 675 female) patients with a fragility hip fracture were identified. In the hip fracture patients, overall mortality rate after 1 year was 21.3% (males 30.7% and females 19.1%, P < 0.005) and, after 5 years, 59.0% (males 70.0% and females 54.6%, P < 0.005). The corresponding figures for matched controls were 5.6% (males 5.9%, females 5.4%, P = 0.6) and 24.9% (males 25.9%, females 24.5%, P = 0.4), respectively. A statistically significant difference was seen in the log-rank statistical analysis between hip fracture patients and controls, both in males (P < 0.0005) and females (P < 0.0005), and for age groups 50-80 years (P < 0.0005) and 80 years and older (P < 0.0005).

Conclusion: Mortality in males and females with hip fractures is high not only in the first year after fracture, but remains higher than in the background population during 5 years of follow-up. The high mortality in hip fracture patients remains a challenge both in middle-aged and elderly individuals. Optimization of post-fracture treatment and care could reduce mortality of hip fracture in middle-aged and elderly individuals.

Keywords: hip fracture; mortality; population-based study; survival.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Kaplan–Meier survival analysis in males and females with a fragility hip fracture in 2004–2005 in southern Norway compared to matched controls.
Figure 2
Figure 2
Kaplan–Meier survival analyses in males and females with a fragility hip fracture in 2004–2005 in southern Norway. Notes: (A) Age group 50–80 years; (B) age group 80+ years.
Figure 3
Figure 3
Kaplan–Meier survival analysis in patients with a fragility hip fracture in 2004–2005 in southern Norway (indicated with Yes) compared to matched controls (indicated with No).
See this image and copyright information in PMC

References

    1. Haentjens P, Magaziner J, Colón-Emeric CS, et al. Meta-analysis: excess mortality after hip fracture among older women and men. Ann Intern Med. 2010;152(6):380–390. - PMC - PubMed
    1. Abrahamsen B, van Staa T, Ariely R, Olson M, Cooper C. Excess mortality following hip fracture: a systematic epidemiological review. Osteoporos Int. 2009;20(10):1633–1650. - PubMed
    1. Magaziner J, Lydick E, Hawkes W, et al. Excess mortality attributable to hip fracture in white women aged 70 years and older. Am J Public Health. 1997;87(10):1630–1636. - PMC - PubMed
    1. Forsen L, Sogaard AJ, Meyer HE, Edna T, Kopjar B. Survival after hip fracture: short- and long-term excess mortality according to age and gender. Osteoporos Int. 1999;10(1):73–78. - PubMed
    1. Empana JP, Dargent-Molina P, Bréart G, EPIDOS Group Effect of hip fracture on mortality in elderly women: the EPIDOS prospective study. J Am Geriatr Soc. 2004;52(5):685–690. - PubMed

Publication types