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. 2013 May;13(2):318-22.
doi: 10.12816/0003241. Epub 2013 May 9.

Severe Pulmonary Involvement in Leptospirosis: Alternate antibiotics and systemic steroids

B Jayakrishnan  1 , Fatma Ben Abid, Abdullah Balkhair, Juma K Alkaabi, Omar A Al-Rawas, Jojy George, Khalfan Al-Zeedy
Affiliations

Severe Pulmonary Involvement in Leptospirosis: Alternate antibiotics and systemic steroids

B Jayakrishnan et al. Sultan Qaboos Univ Med J. 2013 May.

Abstract

Pulmonary complications in leptospirosis, though common, are often unrecognized in a non-endemic area. We report here a patient with leptospirosis and severe pulmonary involvement who was treated with meropenem (1 g every 8 hours), moxifloxacin (400 mg once daily), and high doses of corticosteroids. Systemic steroids were continued for 3 months because of persistent pulmonary lesions.

Keywords: Case report; Human ARDS; Leptospirosis; Oman; Steroids.

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Figures

Figure 1 A–D:
Figure 1 A–D:
(A) Chest radiograph on admission to our centre showing bilateral uniform opacities with a peripheral distribution; (B) Computed tomography (CT) image showing bilateral symmetrical opacities with interlobular and centrilobular septal thickening and micronodularities; (C) CT scan during follow-up one month after discharge showing persistent interstitial shadows; (D) CT scan showing total resolution of the opacities but with minimal localised interstitial shadows on the right side.
See this image and copyright information in PMC

References

    1. Carvalho CR, Bethlem EP. Pulmonary complications of leptospirosis. Clin Chest Med. 2002;23:469–78. - PubMed
    1. Helmerhorst HJ, van Tol EN, Tuinman PR, de Vries PJ, Hartskeerl RA, Grobusch MP, et al. Severe pulmonary manifestation of leptospirosis. Neth J Med. 2012;70:215–21. - PubMed
    1. Assimakopoulos SF, Fligou F, Marangos M, Zotou A, Psilopanagioti A, Filos KS. Anicteric leptospirosis-associated severe pulmonary hemorrhagic syndrome: A case series study. Am J Med Sci. 2012;344:326–9. - PubMed
    1. Tanomkiat W, Poonsawat P. Pulmonary radiographic findings in 118 leptospirosis patients. Southeast Asian J Trop Med Public Health. 2005;36:1247–51. - PubMed
    1. Marchiori E, Muller NL. Leptospirosis of the lung: High-resolution computed tomography findings in five patients. J Thorac Imaging. 2002;17:151–3. - PubMed

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