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. 2013 Aug;41(4):887-8.
doi: 10.1042/BST20130092.

Talks about TORCs: recent advancesin target of rapamycin signalling. On mTOR nomenclature

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Talks about TORCs: recent advancesin target of rapamycin signalling. On mTOR nomenclature

Michael N Hall. Biochem Soc Trans. 2013 Aug.

Abstract

In the present article, I discuss recent developments in the naming of the TOR (target of rapamycin) protein. In particular, I address the issue of mammalian target of rapamycin (mTOR) versus the newer mechanistic target of rapamycin (MTOR). mTOR is the name given by the TOR community almost two decades ago and widely used ever since. MTOR is a name recently imposed on the TOR community by database curators and used mainly by newcomers. I argue that MTOR is causing needless confusion in the field, and conclude that one should use the name mTOR.

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