Calcifying pseudoneoplasm of the neuraxis overlying the corpus callosum: a case report and review of the literature

Abstract

Calcifying pseudoneoplasms of the neuraxis (CPN), also known as fibroosseous lesions, are slow-growing lesions that can occur in a variety of regions of the central nervous system (CNS). These lesions are especially rare, with no more than 30 intracranial cases reported in the literature. Due to its non-malignant/non-metastatic course, one can expect an excellent prognosis with a successful complete resection. However, depending on the location of presentation within the CNS, CPN can present unique challenges in diagnosis and subsequently, the treatment course undertaken. We present a case of an intracranial, extra-axial CPN in a 49-year-old woman, the second to be reported in this location ever and first in 30 years, and detail the clinical, histopathologic and radiological features of a CPN along with a review of the literature.