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Editorial
. 2014 May;85(5):476.
doi: 10.1136/jnnp-2013-305726. Epub 2013 Jul 18.

A roadmap for genetic testing in ALS

Editorial

A roadmap for genetic testing in ALS

Bryan J Traynor. J Neurol Neurosurg Psychiatry. 2014 May.
No abstract available

Keywords: Genetics; Motor Neuron Disease.

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Comment on

  • Genetic counselling in ALS: facts, uncertainties and clinical suggestions.
    Chiò A, Battistini S, Calvo A, Caponnetto C, Conforti FL, Corbo M, Giannini F, Mandrioli J, Mora G, Sabatelli M; ITALSGEN Consortium; Ajmone C, Mastro E, Pain D, Mandich P, Penco S, Restagno G, Zollino M, Surbone A. Chiò A, et al. J Neurol Neurosurg Psychiatry. 2014 May;85(5):478-85. doi: 10.1136/jnnp-2013-305546. Epub 2013 Jul 6. J Neurol Neurosurg Psychiatry. 2014. PMID: 23833266 Review.

References

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    1. Dejesus-Hernandez M, Mackenzie IR, Boeve BF, et al. Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS. Neuron. 2011;72:245–56. - PMC - PubMed
    1. Majounie E, Renton AE, Mok K, et al. Frequency of the C9ORF72 hexanucleotide repeat expansion in patients with amyotrophic lateral sclerosis and frontotemporal dementia: a cross-sectional study. Lancet Neurol. 2012;11:323–30. - PMC - PubMed
    1. Chiò A, Borghero G, Restagno G, et al. Clinical characteristics of patients with familial amyotrophic lateral sclerosis carrying the pathogenic GGGGCC hexanucleotide repeat expansion of C9ORF72. Brain. 2012;135:784–93. - PMC - PubMed