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Case Reports
. 2013 May;17(3):521-3.
doi: 10.4103/2230-8210.111676.

Thymic hyperplasia in Graves' disease

Narendra Kotwal  1 , Yashpal Singh, Anil Menon, Vineet Behera
Affiliations
Case Reports

Thymic hyperplasia in Graves' disease

Narendra Kotwal et al. Indian J Endocrinol Metab. 2013 May.

Abstract

Graves' disease is an autoimmune thyroid condition characterized by the production of autoantibodies against the thyrotropin receptor. It is known to be associated with autoimmune conditions such as myasthenia gravis, Addison's disease, type 1 diabetes mellitus, and vitiligo. We present a case of rare autoimmune association of Graves' disease with thymic hyperplasia which regressed after treatment with antithyroid drugs. Exact pathophysiology of thymic hyperplasia in Graves' is not well understood; it is likely to be the result of rather than the cause of Graves' disease.

Keywords: Antithyroid drugs; Graves’ disease; autoimmune condition; thymic hyperplasia.

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Conflict of interest statement

Conflict of Interest: None declared

Figures

Figure 1
Figure 1
CECT scan chest of the patient showing a 5.6 × 2.1 × 6.0 cm mass in the anterior mediastinum suggestive of thymic hyperplasia
Figure 2
Figure 2
Repeat CECT scan chest of the patient after treatment with antithyroid drugs showing regression in size of the thymus (2.4 × 1.2 × 3.0 cm)
See this image and copyright information in PMC

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