Born equal: dual safeguards for daughter cell size symmetry
- PMID: 23870117
- DOI: 10.1016/j.cell.2013.06.035
Born equal: dual safeguards for daughter cell size symmetry
Abstract
Development and homeostasis require repeated symmetric cell divisions, which in turn depend on a centered mitotic spindle. In this issue, Kiyomitsu and Cheeseman uncover two mechanisms that ensure correct spindle positioning in anaphase: cortical dynein for pulling the spindle to the cell center and asymmetric membrane elongation that adjusts the position of the cell center to the cleavage plane.
Copyright © 2013 Elsevier Inc. All rights reserved.
Comment on
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Cortical dynein and asymmetric membrane elongation coordinately position the spindle in anaphase.Cell. 2013 Jul 18;154(2):391-402. doi: 10.1016/j.cell.2013.06.010. Cell. 2013. PMID: 23870127 Free PMC article.
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