Noncoding roX RNA remodeling triggers fly dosage compensation complex assembly
- PMID: 23870139
- DOI: 10.1016/j.molcel.2013.07.007
Noncoding roX RNA remodeling triggers fly dosage compensation complex assembly
Abstract
Spreading of dosage compensation over the X chromosome in Drosophila males requires the noncoding roX1 and roX2 RNAs. In this issue, Ilik et al. (2013) and Maenner et al. (2013) show that these RNAs contain discrete binding sites that are remodeled during assembly of the dosage compensation complex.
Copyright © 2013 Elsevier Inc. All rights reserved.
Comment on
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Tandem stem-loops in roX RNAs act together to mediate X chromosome dosage compensation in Drosophila.Mol Cell. 2013 Jul 25;51(2):156-73. doi: 10.1016/j.molcel.2013.07.001. Mol Cell. 2013. PMID: 23870142 Free PMC article.
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ATP-dependent roX RNA remodeling by the helicase maleless enables specific association of MSL proteins.Mol Cell. 2013 Jul 25;51(2):174-84. doi: 10.1016/j.molcel.2013.06.011. Mol Cell. 2013. PMID: 23870143
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