Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2013;18(8):926-32.
doi: 10.1634/theoncologist.2013-0072. Epub 2013 Jul 19.

RAS mutations in thyroid cancer

Affiliations
Review

RAS mutations in thyroid cancer

Gina M Howell et al. Oncologist. 2013.

Abstract

In recent years, our understanding of the genetic alterations underlying thyroid oncogenesis has greatly expanded. The use of molecular markers, including RAS, in the management of thyroid carcinoma is also increasing. This review summarizes the current literature surrounding RAS and discusses its potential as a diagnostic and prognostic indicator in the management of thyroid cancer.

Keywords: Molecular markers; RAS; Thyroid cancer; Thyroid nodules.

PubMed Disclaimer

Conflict of interest statement

Disclosures of potential conflicts of interest may be found at the end of this article.

References

    1. Davies L, Welch HG. Increasing incidence of thyroid cancer in the United States, 1973–2002. JAMA. 2006;295:2164–2167. - PubMed
    1. DeLellis RA, Lloyd RV, Heitz PU, et al., editors. Pathology and Genetics of Tumours of Endocrine Organs. Lyon, France: IARC Press; 2004. World Health Organization Classification of Tumours.
    1. Nikiforova MN, Nikiforov YE. Molecular Testing of Thyroid FNA Samples. In: Nikiforov YE, Biddinger PW, Thompson LDR, editors. Diagnostic Pathology and Molecular Genetics of the Thyroid. Baltimore, MD: Lippincott Williams & Wilkins; 2009. pp. 94–102.
    1. Nikiforov YE, Nikiforova MN. Molecular genetics and diagnosis of thyroid cancer. Nat Rev Endocrinol. 2011;7:569–580. - PubMed
    1. Nikiforov YE. Thyroid carcinoma: Molecular pathways and therapeutic targets. Mod Pathol. 2008;21:S37–43. - PMC - PubMed