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Case Reports
. 2013 Apr;29(2):248-51.
doi: 10.4103/0970-9185.111656.

Aortic valve replacement in a patient with systemic lupus erythematosus

Affiliations
Case Reports

Aortic valve replacement in a patient with systemic lupus erythematosus

Bhuvnesh Kansara et al. J Anaesthesiol Clin Pharmacol. 2013 Apr.

Abstract

Valvular heart disease in systemic lupus erythematosus (SLE) is associated with substantial morbidity and mortality. Current therapy includes symptomatic measures and valve replacement. SLE can present major challenges because of accrued organ damage, coagulation defects and complex management regimes. The peri-operative goals are to maintain strict asepsis, avoid use of nephrotoxic drugs and thereby renal insult, and to promote early ambulation post-operatively.

Keywords: Anesthesia; aortic valve replacement; systemic lupus erythematosus.

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Conflict of interest statement

Conflict of Interest: None declared.

References

    1. Danchenko N, Satia JA, Anthony MS. Epidemiology of systemic lupus erythematosus: A comparison of worldwide disease burden. Lupus. 2006;15:308–18. - PubMed
    1. Smith EL, Shmerling RH. The American College of Rheumatology criteria for the classification of systemic lupus erythematosus: Strengths, weaknesses, and opportunities for improvement. Lupus. 1999;8:586–95. - PubMed
    1. Libman E, Sacks B. A hitherto undescribed form of valvular and mural endocarditis. Arch Intern Med. 1924;33:701–37.
    1. Gorki H, Malinovski V, Stanbridge RD. The antiphospholipid syndrome and heart valve surgery. Eur J Cardiothorac Surg. 2008;33:168–81. - PubMed
    1. Lin CH, Lee ML, Hsu RB. Cardiac surgery in patients with systemic lupus erythematosus. Interact Cardiovasc Thorac Surg. 2005;4:618–21. - PubMed

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