Uterus transplantation from a deceased donor

Abstract

Objective: To demonstrate the technique for uterus retrieval and transplantation from a multiorgan donor.

Design: Video presentation of our case report. The video uses animation to demonstrate the technique. Institutional Review Board (IRB) approval was obtained.

Setting: University hospital.

Patient(s): A 21-year-old woman with complete müllerian agenesis.

Intervention(s): Uterus allotransplantation has been performed from a deceased donor.

Main outcome measure(s): Acquirement of cyclic menstrual function.

Result(s): This video demonstrates the technique for uterus retrieval, perfusion, and transplantation. The recipient patient has been monitored regularly for vascular flow, immunosuppression, and infection control since the operation.

Conclusion(s): Uterus transplantation requires extensive evaluation of the recipient and donor by an experienced multidisciplinary transplantation team both pre- and postoperatively. It has major risks related to surgery, immunosuppression, and pregnancy. Uterus transplantation might be considered promising only after the birth of a near-term healthy baby.

Keywords: Uterus transplantation; deceased donor; uterine factor infertility.