Separating wheat from chaff: examining the obesity paradox in the critically ill
- PMID: 23890365
- PMCID: PMC4057110
- DOI: 10.1186/cc12798
Separating wheat from chaff: examining the obesity paradox in the critically ill
Abstract
Obesity is an increasing burden globally. In the general population, the obese have an increased mortality risk. Regarding the critically ill, a growing body of literature supports the obesity paradox, the notion that obesity confers a protective effect in certain disease states. However, the paucity of methodologically sound trials prevents definitive interpretation and may obscure risks.
Comment on
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One size does not fit all in severe infection: obesity alters outcome, susceptibility, treatment, and inflammatory response.Crit Care. 2013 Jun 20;17(3):R122. doi: 10.1186/cc12794. Crit Care. 2013. PMID: 23786836 Free PMC article. Clinical Trial.
References
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- World Health Organization. Obesity and overweight: Fact sheet no. 311. http://www.who.int/mediacentre/factsheets/fs311/en/
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