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Figure 1. Current approaches of anticancer immunochemotherapy.…
Figure 1. Current approaches of anticancer immunochemotherapy. Among the articles published in OncoImmunology from January…
Figure 1. Current approaches of anticancer immunochemotherapy. Among the articles published in OncoImmunology from January 2012 to March 2013, all those describing or commenting the sequential or concomitant administration of distinct immunotherapeutic or chemotherapeutic regimens (both in preclinical and clinical settings) have been identified, and such combinatorial approaches have been classified based on the most prominent immunostimulatory activity of their components. The size of inward bulges and the weight of central connectors reflects the relative proportion of homologous (involving the use of two distinct molecules that exert immunostimulatory effects via the same general mechanism) and heterologous (involving the administration of two agents that promote anticancer immune responses via distinct general mechanisms) combinatorial approaches to immunochemotherapy, respectively.
Galluzzi L, Senovilla L, Zitvogel L, Kroemer G. The secret ally: immunostimulation by anticancer drugs. Nat Rev Drug Discov. 2012;11:215–33. doi: 10.1038/nrd3626.
-
DOI
-
PubMed
Zitvogel L, Kepp O, Kroemer G. Immune parameters affecting the efficacy of chemotherapeutic regimens. Nat Rev Clin Oncol. 2011;8:151–60. doi: 10.1038/nrclinonc.2010.223.
-
DOI
-
PubMed
Prendergast GC. Immunological thought in the mainstream of cancer research: Past divorce, recent remarriage and elective affinities of the future. Oncoimmunology. 2012;1:793–7. doi: 10.4161/onci.20909.
-
DOI
-
PMC
-
PubMed
Lesterhuis WJ, Haanen JB, Punt CJ. Cancer immunotherapy--revisited. Nat Rev Drug Discov. 2011;10:591–600. doi: 10.1038/nrd3500.
-
DOI
-
PubMed
Vanneman M, Dranoff G. Combining immunotherapy and targeted therapies in cancer treatment. Nat Rev Cancer. 2012;12:237–51. doi: 10.1038/nrc3237.
-
DOI
-
PMC
-
PubMed