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. 2013 Jul 29;2013(7):CD004917.
doi: 10.1002/14651858.CD004917.pub3.

Interventions for infantile esotropia

Sue Elliott  1 , Ayad Shafiq
Affiliations

Interventions for infantile esotropia

Sue Elliott et al. Cochrane Database Syst Rev. .

Update in

  • Interventions for infantile esotropia.
    Mehner L, Ng SM, Singh J. Mehner L, et al. Cochrane Database Syst Rev. 2023 Jan 16;1(1):CD004917. doi: 10.1002/14651858.CD004917.pub4. Cochrane Database Syst Rev. 2023. PMID: 36645238 Free PMC article.

Abstract

Background: Infantile esotropia (IE) is the inward deviation of the eye. Various aspects of the clinical management of IE are unclear; mainly, the most effective type of intervention and the age at intervention.

Objectives: The objective of this review was to assess the effectiveness of various surgical and non-surgical interventions for IE and to determine the significance of age at treatment with respect to outcome.

Search methods: We searched CENTRAL (which contains the Cochrane Eyes and Vision Group Trials Register) (The Cochrane Library 2013, Issue 5), Ovid MEDLINE, Ovid MEDLINE In-Process and Other Non-Indexed Citations, Ovid MEDLINE Daily, Ovid OLDMEDLINE, (January 1950 to June 2013), EMBASE (January 1980 to June 2013), Latin American and Caribbean Literature on Health Sciences (LILACS) (January 1982 to June 2013), the metaRegister of Controlled Trials (mRCT) (www.controlled-trials.com), ClinicalTrials.gov (www.clinicaltrials.gov) and the WHO International Clinical Trials Registry Platform (ICTRP) (www.who.int/ictrp/search/en). We did not use any date or language restrictions in the electronic searches for trials. We last searched the electronic databases on 10 June 2013. We manually searched the conference proceedings of the European Strabismological Association (ESA) (1975 to 1997, 1999 to 2002), International Strabismological Association (ISA) (1994) and American Academy of Paediatric Ophthalmology and Strabismus meeting (AAPOS) (1995 to 2003). Efforts were made to contact researchers who are active in the field for information about further published or unpublished studies.

Selection criteria: We included randomised trials comparing any surgical or non-surgical intervention for infantile esotropia.

Data collection and analysis: Each review author independently assessed study abstracts identified from the electronic and manual searches.

Main results: No studies were found that met our selection criteria and therefore none were included for analysis.

Authors' conclusions: The main body of literature on interventions for IE are either retrospective studies or prospective cohort studies. It has not been possible through this review to resolve the controversies regarding type of surgery, non-surgical intervention and age of intervention. There is clearly a need for good quality trials to be conducted in these areas to improve the evidence base for the management of IE.

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Conflict of interest statement

None known.

Update of

References

References to studies excluded from this review

Arnoult 1976 {published data only}
    1. Arnoult JB, Yeshurun O, Mazow ML. Comparative study of the surgical management of congenital esotropia of 50 prism dioptres or less. Journal of Pediatric Ophthalmology 1976;13(3):129‐31. - PubMed
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Polling 2009 {published data only}
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References to other published versions of this review

Elliott 2005
    1. Elliott S, Shafiq A. Interventions for infantile esotropia. Cochrane Database of Systematic Reviews 2005, Issue 1. [DOI: 10.1002/14651858.CD004917.pub2] - DOI - PubMed

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