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Comment
. 2013 Sep;10(9):508-9.
doi: 10.1038/nrgastro.2013.136. Epub 2013 Jul 30.

Viral hepatitis: Cell-culture-derived HCV--a promising vaccine antigen

Judith M Gottwein  1 , Jens Bukh
Affiliations
Comment

Viral hepatitis: Cell-culture-derived HCV--a promising vaccine antigen

Judith M Gottwein et al. Nat Rev Gastroenterol Hepatol. 2013 Sep.

Abstract

With millions of humans infected yearly with HCV, leading to cirrhosis and cancer, a vaccine is urgently needed. Cultured virus particles constitute the antigen in most antiviral vaccines. A study in mice demonstrated induction of neutralizing antibodies by immunization with cell-culture-derived HCV, providing new possibilities for vaccine development.

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References

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