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Comment
. 2013 Jul;25(7):2382.
doi: 10.1105/tpc.113.250713. Epub 2013 Jul 29.

The plant cell reviews aspects of microRNA and PhasiRNA regulatory function

Nancy A Eckardt  1
Affiliations
Comment

The plant cell reviews aspects of microRNA and PhasiRNA regulatory function

Nancy A Eckardt. Plant Cell. 2013 Jul.
No abstract available

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Figures

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Transcription of MIR genes produces pri-miRNAs that are recruited to dicing bodies and cleaved into miRNAs by the Dicer enzyme (mainly DCL1 in Arabidopsis). Depending on the MIR gene involved (and a host of other factors), the mature miRNAs then go on to participate in translational inhibition (A), transcript cleavage (B), or phasi/tasiRNA production (C). TasiRNAs go on to associate with AGO1 and participate in cleavage of other mRNAs.
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References

    1. Fei Q., Xia R., Meyers B.C. (2013). Phased, secondary siRNAs in post-transcriptional regulatory networks. Plant Cell 25: 2400–2415 - PMC - PubMed
    1. Lee R.C., Feinbaum R.L., Ambros V. (1993). The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell 75: 843–854 - PubMed
    1. Rogers K., Chen X. (2013). Biogenesis, turnover, and mode of action of plant microRNAs. Plant Cell 25: 2383–2399 - PMC - PubMed
    1. Wightman B., Ha I., Ruvkun G. (1993). Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans. Cell 75: 855–862 - PubMed

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