Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2013;22(6):567-70.
doi: 10.1159/000351884. Epub 2013 Jul 26.

Heart rate recovery is impaired in patients with psoriasis

Bahadir Sarli  1 , Yasemin Dogan, Ahmet Oguz Baktir, Hayrettin Saglam, Huseyin Arinc, Serkan Kurtul, Atıl Avci, Levent Cinar, Mahmut Akpek, Mehmet G Kaya
Affiliations

Heart rate recovery is impaired in patients with psoriasis

Bahadir Sarli et al. Med Princ Pract. 2013.

Abstract

Objective: The aim of this study was to investigate the relationship between psoriasis and heart rate recovery (HRR) index.

Patients and methods: A total of 50 patients with a diagnosis of psoriasis and 32 healthy volunteers were included in the study. In all patients, a stress test was performed to calculate the HRR index in a manner which aimed to reach the age-specific maximum heart rate. HRR indices were calculated in all patients and controls.

Results: HRR (beats/minute) indices after the 1st (HRR1, 26 ± 10 vs. 33 ± 8, p = 0.002), 2nd (44 ± 11 vs. 50 ± 6, p = 0.002), 3rd (51 ± 7 vs. 63 ± 8, p < 0.001), 4th (54 ± 7 vs. 65 ± 8, p < 0.001) and 5th (57 ± 8 vs. 70 ± 10, p < 0.001) minutes of the recovery period were significantly lower in the psoriasis group compared to healthy controls. In addition, HRR1 was significantly correlated with duration of psoriasis (r = 0.541, p < 0.001) and psoriasis area and severity index score (r = 0.511, p < 0.001).

Conclusion: HRR was lower in patients with psoriasis. Given the prognostic value of this test, patients with psoriasis might be at risk for future cardiovascular events and cardiovascular mortality.

PubMed Disclaimer

Comment in

References

    1. Hsu LN, Armstrong AW. Psoriasis and autoimmune disorders: a review of the literature. J Am Acad Dermatol. 2012;67:1076–1079. - PubMed
    1. Friedewald VE, Cather JC, Gelfand JM, et al. AJC editor's consensus: psoriasis and coronary artery disease. Am J Cardiol. 2008;102:1631–1643. - PubMed
    1. Wakkee M, Thio HB, Prens EP, et al. Unfavorable cardiovascular risk profiles in untreated and treated psoriasis patients. Atherosclerosis. 2007;190:1–9. - PubMed
    1. Pasternak RC, Abrams J, Greenland P, et al. 34th Bethesda Conference: Task Force 1 – identification of coronary heart disease risk: is there a detection gap? J Am Coll Cardiol. 2003;411:863–1874. - PubMed
    1. Morshedi-Meibodi A, Larson MG, Levy D, et al. Heart rate recovery after treadmill exercise testing and risk of cardiovascular disease events (the Framingham Heart Study) Am J Cardiol. 2002;90:848–852. - PubMed