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Case Reports
. 2013 Oct;51(10):3454-5.
doi: 10.1128/JCM.01018-13. Epub 2013 Jul 31.

Rhombencephalitis caused by Francisella tularensis

M Barbaz  1 , C Piau, J M Tadie, I Pelloux, S Kayal, P Tattevin, Y Le Tulzo, M Revest
Affiliations
Case Reports

Rhombencephalitis caused by Francisella tularensis

M Barbaz et al. J Clin Microbiol. 2013 Oct.

Abstract

Common presentations of tularemia include pneumonia and ulceroglandular, oropharyngeal, or typhoidal disease. Neuromeningeal involvement is extremely rare. We report a case of a severe rhombencephalitis due to Francisella tularensis. Diagnosis was possible thanks to a very precise interview, and the patient dramatically improved after specific antibiotherapy.

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Figures

Fig 1
Fig 1
(a) Axial T1-gadolinium MR brain scan showing brainstem hypersignal; (b) axial T1-gadolinium MR brain scan control at day 68.
See this image and copyright information in PMC

References

    1. Mailles A, Stahl JP. 2009. Infectious encephalitis in France in 2007: a national prospective study. Clin. Infect. Dis. 49:1838–1847 - PubMed
    1. Rolain JM, Colson P, Raoult D. 2007. Recycling of chloroquine and its hydroxyl analogue to face bacterial, fungal and viral infections in the 21st century. Int. J. Antimicrob. Agents 30:297–308 - PMC - PubMed
    1. Fortier AH, Leiby DA, Narayanan RB, Asafoadjei E, Crawford RM, Nacy CA, Melzer MS. 1995. Growth of Francisella tularensis LVS in macrophages: the acidic intracellular compartment provides essential iron required for growth. Infect. Immun. 63:1478–1483 - PMC - PubMed
    1. Hofinger DM, Cardona L, Mertz GJ, Davis LE. 2009. Tularemic meningitis in the United States. Arch. Neurol. 66:523–527 - PubMed
    1. Maurin M, Pelloux I, Brion JP, Del Bano JN, Picard A. 2011. Human tularemia in France, 2006–2010. Clin. Infect. Dis. 53:e133–e141 - PubMed

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