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. 2013 Aug;108(5):657-60.
doi: 10.1590/0074-0276108052013019.

Prevalence of occult hepatitis B virus infection in kidney transplant recipients

Cibele Franz  1 , Renata de Mello Perez, Mariano Gustavo Zalis, Ana Carolina Jonard Zalona, Pedro Túlio Monteiro de Castro e Abreu Rocha, Renato Torres Gonçalves, Letícia Cancella Nabuco, Cristiane Alves Villela-Nogueira
Affiliations

Prevalence of occult hepatitis B virus infection in kidney transplant recipients

Cibele Franz et al. Mem Inst Oswaldo Cruz. 2013 Aug.

Abstract

In this cross-sectional study, 207 hepatitis B surface antigen (HBsAg)-negative kidney transplant recipients were evaluated based on demographic and epidemiological data and on the levels of serological markers of hepatitis B virus (HBV) and hepatitis C virus infection and liver enzymes. Patients with HBV or human immunodeficiency virus infection were excluded. Sera were analysed for the presence of HBV-DNA. HBV-DNA was detected in two patients (1%), indicating occult hepatitis B (OHB) infection (the HBV-DNA loads were 3.1 and 3.5 IU/mL in these patients). The results of the liver function tests were normal and no serological markers indicative of HBV infection were detected. The prevalence of OHB infection was low among kidney transplant recipients, most likely due to the low HBsAg endemicity in the general population of the study area.

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