Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2013 Jun;7(6):1152-4.
doi: 10.7860/JCDR/2013/5313.3060. Epub 2013 Jun 1.

A huge primary ovarian leiomyoma with degenerative changes-an unusual

Ranjan Agrawal  1 , Mukta Kumar, Lata Agrawal, Keshav Kumar Agrawal
Affiliations

A huge primary ovarian leiomyoma with degenerative changes-an unusual

Ranjan Agrawal et al. J Clin Diagn Res. 2013 Jun.

Abstract

Primary ovarian leiomyoma is a rare benign tumour of the ovary, which is seen in women who are aged between 20 years to 65 years. Ovarian leiomyomas can be confused with other spindle cell tumours which display gross anatomical and histological similarities. A case of a primary leiomyoma of the ovary in a pre-menopausal female is being presented here, due to its huge size and unusual presentation.

Keywords: Benign; Huge; Ovarian leiomyoma; Primary tumour; Secondary changes.

PubMed Disclaimer

Figures

[Table/Fig-1]:
[Table/Fig-1]:
Gross specimen with multiple irregular pieces obtained after debulking
[Table/Fig-2]:
[Table/Fig-2]:
Leiomyoma with areas of hyaline and myxomatous changes (H&E ×100).
[Table/Fig-3]:
[Table/Fig-3]:
Diffuse positivity of neoplastic cells on Immunohistochemical stain by SMA( smooth muscle actin) (IHC, SMA X100)
[Table/Fig-4]:
[Table/Fig-4]:
Desmin stain showing positive reaction in the neoplastic cells (IHC, Desmin X100)
See this image and copyright information in PMC

References

    1. Safaei A, Khanlari M, Azarpira N, Monabati A. Large ovarian leiomyoma in a postmenopausal woman. Indian J Pathol Microbiol. 2011;54:413–4. PMID: 21623113. - PubMed
    1. Herbut PA. In Gynaecological and obstetrical pathology. 1st edition. Philadelphia: Lea and Febiger; 1953. Ovarian leiomyoma; p. 501.
    1. Lerwill MF, Sung R, Oliva E, Prat J, Young RH. Smooth muscle tumours of the ovary: A clinicopathologic study of 54 cases emphasizing prognostic criteria, histologic variants, and differential diagnosis. Am J Surg Pathol.2. 2004;8:1436–51. PMID: 15489647. - PubMed
    1. Murakami M, Uehara H, Nishimura M, Iwasa T, Ikawa H. A huge ovarian smooth muscle tumour: A case report. J Med Invest. 2010;57:158–62. PMID: 20299756. - PubMed
    1. Wellmann KF. Leiomyoma of the Ovary. Can Med Assoc J. 85(8):429–432. 1961. PMCID: PMC1848262. - PMC - PubMed

LinkOut - more resources