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Comment
. 2013 Jul 29;26(2):120-1.
doi: 10.1016/j.devcel.2013.07.011.

An epigenetic trap involved in olfactory receptor gene choice

Calder Reinsborough  1 , Andrew Chess
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An epigenetic trap involved in olfactory receptor gene choice

Calder Reinsborough et al. Dev Cell. .
Free article

Abstract

Reporting recently in Cell, Lyons et al. (2013) reveal key roles for transient LSD1 histone demethylase activity in activation of a single olfactory receptor allele and suppression of the rest of the olfactory receptor gene family, thereby locking in the expression of a single olfactory receptor per sensory neuron.

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