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. 2014 Aug;86(2):185-9.
doi: 10.1111/cge.12246. Epub 2013 Aug 27.

Gynecologic cancer screening and communication with health care providers in women with Lynch syndrome

A M Burton-Chase  1 , S R Hovick, C C Sun, S Boyd-Rogers, P M Lynch, K H Lu, S K Peterson
Affiliations

Gynecologic cancer screening and communication with health care providers in women with Lynch syndrome

A M Burton-Chase et al. Clin Genet. 2014 Aug.

Abstract

We evaluated knowledge of gynecologic cancer screening recommendations, screening behaviors, and communication with providers among women with Lynch syndrome (LS). Women aged ≥25 years who were at risk for LS-associated cancers completed a semi-structured interview and a questionnaire. Of 74 participants (mean age 40 years), 61% knew the appropriate age to begin screening, 75-80% correctly identified the recommended screening frequency, and 84% reported no previous screening endometrial biopsy. Women initiated discussions with their providers about their LS cancer risks, but many used nonspecific terms or relied on family history. Most were not offered high-risk screening options. While many women were aware of risk-appropriate LS screening guidelines, adherence was suboptimal. Improving communication between women and their providers regarding LS-related gynecologic cancer risk and screening options may help improve adherence.

Keywords: Lynch syndrome; endometrial cancer; mixed methods; ovarian cancer; patient-physician communication.

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Conflict of interest statement

Conflict of interest

The authors declare no conflicts of interest.

References

    1. Backes FJ, Mitchell E, Hampel H, Cohn DE. Endometrial cancer patients and compliance with genetic counseling: room for improvement. Gynecol Oncol. 2011;123(3):532–536. - PubMed
    1. Grover S, Stoffel EM, Mercado RC, et al. Colorectal cancer risk perception on the basis of genetic test results in individuals at risk for Lynch syndrome. J Clin Oncol. 2009;27(24):3981–3986. - PMC - PubMed
    1. Lindor NM, Peterson GM, Hadley DW, et al. Recommendations for the care of individuals with an inherited predisposition to Lynch Syndrome: a systematic review. J Amer Med Assoc. 2006;296:1507–1517. - PubMed
    1. Jrvinen H, Aarnio M, Mustonen H, Aktan-Collan K. Controlled 15-year trial on screening for colorectal cancer in families with hereditary nonpolyposis colorectal cancer. Gastroenterology. 2000;118(5):829–834. - PubMed
    1. Järvinen HJ, Renkonen-Sinisalo L, Aktán-Collán K, Peltomäki P, Aaltonen LA, Mecklin JP. Ten years after mutation testing for Lynch syndrome: cancer incidence and outcome in mutation-positive and mutation-negative family members. J Clin Oncol. 2009;27(28):4793–4797. - PubMed

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