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Comment
. 2013 Aug 1;122(5):624-5.
doi: 10.1182/blood-2013-06-508531.

The endothelial protein C receptor and malaria

Tom van der Poll  1
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Free article
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The endothelial protein C receptor and malaria

Tom van der Poll. Blood. .
Free article

Abstract

In this issue of Blood, Moxon et al provide novel insight into the pathogenesis of cerebral malaria, linking loss of the endothelial protein C receptor (EPCR) on brain vessels, caused by cytoadherent infected erythrocytes, with localized coagulation, inflammation, and disruption of endothelial barrier function.

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