Rewiring immunity: generating a functional thymus from hESCs… are we there yet?
- PMID: 23910077
- DOI: 10.1016/j.stem.2013.07.015
Rewiring immunity: generating a functional thymus from hESCs… are we there yet?
Abstract
Two papers in this issue of Cell Stem Cell have made a significant advance in solving one of the great challenges of modern immunology-resurrecting thymus function through the induction of thymus epithelial cells (TECs) by directed differentiation of human embryonic stem cells (hESCs).
Copyright © 2013 Elsevier Inc. All rights reserved.
Comment on
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Generation of functional thymic epithelium from human embryonic stem cells that supports host T cell development.Cell Stem Cell. 2013 Aug 1;13(2):219-29. doi: 10.1016/j.stem.2013.04.004. Epub 2013 May 16. Cell Stem Cell. 2013. PMID: 23684540 Free PMC article.
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Directed differentiation of human embryonic stem cells into thymic epithelial progenitor-like cells reconstitutes the thymic microenvironment in vivo.Cell Stem Cell. 2013 Aug 1;13(2):230-6. doi: 10.1016/j.stem.2013.06.014. Cell Stem Cell. 2013. PMID: 23910085
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