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Comment
. 2013 Aug 1;13(2):137-8.
doi: 10.1016/j.stem.2013.07.008.

Parental permissions: H19 and keeping the stem cell progeny under control

Margaret A Goodell  1
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Parental permissions: H19 and keeping the stem cell progeny under control

Margaret A Goodell. Cell Stem Cell. .
Free article

Abstract

H19 is shown by Venkatraman et al. (2013), using maternal-allele-specific deletion of the differentially methylated region, to maintain hematopoietic stem cell repopulating ability through a miR-675-Igf1r signaling circuit. This work establishes function in somatic stem cells for another member of a putative imprinted gene network that may influence organismal growth.

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