Transplantable liver organoids made from only three ingredients
- PMID: 23910079
- PMCID: PMC3828077
- DOI: 10.1016/j.stem.2013.07.014
Transplantable liver organoids made from only three ingredients
Abstract
Liver cell therapies using induced pluripotent stem cells (iPSCs) are in development. A recent paper in Nature by Takebe et al. expands the range of liver diseases that could be treated with iPSC-derived hepatocytes by combining them with endothelial and stromal cells to generate organoids that survive and function extrahepatically.
Copyright © 2013 Elsevier Inc. All rights reserved.
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Comment on
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Vascularized and functional human liver from an iPSC-derived organ bud transplant.Nature. 2013 Jul 25;499(7459):481-4. doi: 10.1038/nature12271. Epub 2013 Jul 3. Nature. 2013. PMID: 23823721
References
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