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Comment
. 2013 Aug 1;154(3):477-9.
doi: 10.1016/j.cell.2013.07.010.

A histone modifier's ill-gotten copy gains

Ryan Rickels  1 , Ali Shilatifard
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Free article
Comment

A histone modifier's ill-gotten copy gains

Ryan Rickels et al. Cell. .
Free article

Abstract

Little is known about the molecular machinery that contributes to site-specific copy number variations or how CNVs fit into the chronology of tumor progression. Black et al. (2013) now demonstrate that the overexpression of a histone demethylase induces transient copy gain of specific genomic loci known to harbor proto-oncogenes.

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