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Case Reports
. 2013 Oct;58(2):494-6.
doi: 10.1016/j.jcv.2013.07.011. Epub 2013 Aug 1.

Adult T-cell leukemia/lymphoma triggered by adalimumab

Achilea L Bittencourt  1 , Pedro D Oliveira, Valeria G Bittencourt, Edgar M Carvalho, Lourdes Farre
Affiliations
Case Reports

Adult T-cell leukemia/lymphoma triggered by adalimumab

Achilea L Bittencourt et al. J Clin Virol. 2013 Oct.

Abstract

Here, we describe a 48-year-old woman infected by the human T-cell lymphotropic virus type 1 (HTLV-1) with spondyloarthritis, uveitis, bilateral episcleritis and neurogenic bladder. She had a history of a probable infective dermatitis associated with HTLV-1 (IDH) in childhood. After the use of adalimumab, she developed lymphocytosis and a cutaneous lymphoma associated with IDH. She had the diagnoses of IDH and of chronic adult T-cell leukemia/lymphoma, supported by the demonstration of proviral integration in the cutaneous lesion.

Keywords: Adalimumab; Adult T-cell leukemia/lymphoma; Anti-TNF-α drugs; Infective dermatitis associated with HTLV-1.

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