Corynephage Cog, a virulent bacteriophage of Corynebacterium glutamicum, and its relationship to phi GA1, an inducible phage particle from Brevibacterium flavum

Abstract

The host range of the virulent bacteriophage Cog among several strains of amino acid-producing corynebacteria is limited to Corynebacterium glutamicum LP-6. Cog is a typical corynephage of the Siphoviridae family (B1 morphotype) with an isometric head of 52 nm and a medium length, striated tail of 190 nm. It has a linear genome of 39.7 kb with cohesive ends and 53% G + C; a restriction map is presented, including regions of DNA homology (by hybridization) with the inducible phage particle phi GA1 from Brevibacterium flavum.