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Review
. 2014 Jan;57(1):2-11.
doi: 10.1016/j.molimm.2013.06.013. Epub 2013 Jul 31.

Genetics of ankylosing spondylitis

Philip C Robinson  1 , Matthew A Brown
Affiliations
Review

Genetics of ankylosing spondylitis

Philip C Robinson et al. Mol Immunol. 2014 Jan.

Abstract

Ankylosing spondylitis (AS) is a chronic inflammatory arthritis that affects the spine and sacroiliac joints. It causes significant disability and is associated with a number of other features including peripheral arthritis, anterior uveitis, psoriasis and inflammatory bowel disease (IBD). Significant progress has been made in the genetics of AS have in the last five years, leading to new treatments in trial, and major leaps in understanding of the aetiopathogenesis of the disease.

Keywords: Ankylosing spondylitis; Single nucleotide polymorphism association; Spondyloarthritis.

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