Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2014 Jun;142(6):1231-44.
doi: 10.1017/S0950268813001726. Epub 2013 Aug 7.

Coxiella burnetii seroprevalence and risk factors in sheep farmers and farm residents in The Netherlands

M M A De Lange  1 , B Schimmer  1 , P Vellema  2 , J L A Hautvast  3 , P M Schneeberger  4 , Y T H P Van Duijnhoven  1
Affiliations

Coxiella burnetii seroprevalence and risk factors in sheep farmers and farm residents in The Netherlands

M M A De Lange et al. Epidemiol Infect. 2014 Jun.

Abstract

In this study, Coxiella burnetii seroprevalence was assessed for dairy and non-dairy sheep farm residents in The Netherlands for 2009-2010. Risk factors for seropositivity were identified for non-dairy sheep farm residents. Participants completed farm-based and individual questionnaires. In addition, participants were tested for IgG and IgM C. burnetii antibodies using immunofluorescent assay. Risk factors were identified by univariate, multivariate logistic regression, and multivariate multilevel analyses. In dairy and non-dairy sheep farm residents, seroprevalence was 66·7% and 51·3%, respectively. Significant risk factors were cattle contact, high goat density near the farm, sheep supplied from two provinces, high frequency of refreshing stable bedding, farm started before 1990 and presence of the Blessumer breed. Most risk factors indicate current or past goat and cattle exposure, with limited factors involving sheep. Subtyping human, cattle, goat, and sheep C. burnetii strains might elucidate their role in the infection risk of sheep farm residents.

PubMed Disclaimer

References

    1. Maurin M, Raoult D. Q fever. Clinical Microbiology Reviews 1999; 12: 518–553. - PMC - PubMed
    1. Marrie TJ, et al. Truckin' pneumonia–an outbreak of Q fever in a truck repair plant probably due to aerosols from clothing contaminated by contact with newborn kittens. Epidemiology and Infection 1989; 102: 119–127. - PMC - PubMed
    1. Gonder JC, et al. Cynomolgus monkey model for experimental Q fever infection. Journal of Infectious Diseases 1979; 139: 191–196. - PubMed
    1. Raoult D, et al. Q fever 1985–1998. Clinical and epidemiologic features of 1,383 infections. Medicine (Baltimore) 2000; 79: 109–123. - PubMed
    1. van der Hoek W, et al. Shifting priorities in the aftermath of a Q fever epidemic in 2007 to 2009 in The Netherlands: from acute to chronic infection. Eurosurveillance 2012; 17: pii=20059. - PubMed

Publication types

MeSH terms