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. 2013 Aug 7;19(29):4781-5.
doi: 10.3748/wjg.v19.i29.4781.

Influence of endoscopic submucosal dissection on esophageal motility

Bao-Guo Bu  1 , En-Qiang Linghu, Hui-Kai Li, Xiao-Xiao Wang, Rong-Bin Guo, Li-Hua Peng
Affiliations

Influence of endoscopic submucosal dissection on esophageal motility

Bao-Guo Bu et al. World J Gastroenterol. .

Abstract

Aim: To assess esophageal motility after esophageal endoscopic submucosal dissection (ESD).

Methods: Twelve patients (6 men and 6 women) aged 53-64 years (mean age, 58 years) who underwent regular examination 3-12 mo after esophageal ESD for neoplasms of the esophageal body were included in this study. The ESD procedure was performed under deep sedation using a combination of propofol and fentanyl, and involved a submucosal injection to lift the lesion and use of a dual-knife and an insulated-tip knife to create a circumferential incision around the lesion extending into the submucosa. Esophageal motility was examined using a high-resolution manometry system. Dysphagia was graded using a five-point scale according to the Mellow and Pinkas scoring system. Patient symptoms and the results of esophageal manometry were then analyzed.

Results: Of the 12 patients enrolled, 1 patient had grade 2 dysphagia, 1 patient had grade 1 dysphagia, and 3 patients complained of sporadic dysphagia. Ineffective esophageal motility was observed in 5 of 6 patients with above semi-circumference of resection extension. Of these 5 patients, 1 patient complained of grade 2 dysphagia (with esophageal stricture), one patient complained of grade 1 dysphagia, and 3 patients complained of sporadic dysphagia. Normal esophageal body manometry was observed in all 6 patients with below semi-circumference of resection extension. The 6 patients with normal esophageal motility did not complain of dysphagia.

Conclusion: Extensive esophageal ESD may cause esophageal dysmotility in some patients, and might also have an influence on dysphagia although without esophageal stricture.

Keywords: Dysphagia; Endoscopic submucosal dissection; Esophageal manometry; Esophageal neoplasm; Ineffective esophageal motility.

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Figures

Figure 1
Figure 1
Segmental simultaneous wave and decreased amplitude in endoscopic submucosal dissection scar site.
See this image and copyright information in PMC

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