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Meta-Analysis
. 2013 Sep;112(5):655-63.
doi: 10.1111/j.1464-410X.2012.11741.x. Epub 2013 Mar 4.

De novo erectile dysfunction after anterior urethroplasty: a systematic review and meta-analysis

Sarah D Blaschko  1 , Melissa T Sanford, Nadya M Cinman, Jack W McAninch, Benjamin N Breyer
Affiliations
Meta-Analysis

De novo erectile dysfunction after anterior urethroplasty: a systematic review and meta-analysis

Sarah D Blaschko et al. BJU Int. 2013 Sep.

Abstract

Objective: To evaluate the likelihood of developing de novo erectile dysfunction (ED) after anterior urethroplasty and to determine if this likelihood is influenced by age, stricture length, number of previous procedures or timing of evaluation.

Materials and methods: PubMed, Embase, Cochrane, and Google Scholar databases were searched for the terms 'urethroplasty', 'urethral obstruction', 'urethral stricture', 'sexual function', 'erection', 'erectile function', 'erectile dysfunction', 'impotence' and 'sexual dysfunction'. Two reviewers evaluated articles for inclusion based on predetermined criteria.

Results: In a meta-analysis of 36 studies with a total of 2323 patients, de novo ED was rare, with an incidence of 1%. In studies that assessed postoperative erectile function at more than one time point, ED was transient and resolved at between 6 and 12 months in 86% of cases.

Conclusions: Men should be counselled regarding the possibility of transient or permanent de novo ED after anterior urethroplasty procedures. Increasing mean age was associated with an increased likelihood of de novo ED, but this was not statistically significant.

Keywords: erectile dysfunction; meta-analysis; systematic review; urethroplasty.

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Figures

Fig. 1
Fig. 1
Flow chart of inclusion and exclusion of studies for the meta-analysis.
Fig. 2
Fig. 2
Forest plot of de novo ED after anterior urethroplasty across all studies.
See this image and copyright information in PMC

Comment in

References

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