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. 2010 Apr;11(1):17-24.

Prevalence of Iron Deficiency Anemia among Iranian Pregnant Women; a Systematic Review and Meta-analysis

Barooti Esmat  1 , Rezazadehkermani Mohammad, Sadeghirad Behnam, Motaghipisheh Shahrzad, Tayeri Soodabeh, Arabi Minoo, Salahi Saman, Haghdoost Ali-Akbar
Affiliations

Prevalence of Iron Deficiency Anemia among Iranian Pregnant Women; a Systematic Review and Meta-analysis

Barooti Esmat et al. J Reprod Infertil. 2010 Apr.

Abstract

Introduction: Anemia, particularly Iron Deficiency Anemia (IDA), is the most common hematological disorder during pregnancy with considerable complications in both mothers and fetuses. The estimation of anemia prevalence is an important step for health policy makers. Despite being considered a hot topic in epidemiological studies in Iran for the last twenty years, lack of a comprehensive overview on the findings encouraged the authors to carry out this study.

Materials and methods: All published papers in main national and international databases were systematically searched for some specific keywords to find the related studies between the years 1993 and 2007. All published studies which had reported the prevalence of anemia were included in the study except studies on refugees, patients undergoing hemodialysis, patients with thalassemia or cancer or other selective sub-populations. Two trained reviewers independently assessed the inclusion/exclusion criteria and the quality of the selected papers, summarized them and eventually analyzed the data.

Results: Ten eligible papers including 11,037 participants were entered into the analysis. The maximum and minimum reported prevalence rates of anemia during pregnancy were 4.3% and 21.5%, respectively. The overall estimate of anemia prevalence in Iranian pregnant women was 13.6 (95% CI: 8.3 - 18.9). Excluding the only out-layer from the meta-analysis, the overall estimated prevalence was 12.4% (95% CI: 9.6% - 17.9%).

Conclusion: The prevalence of anemia in Iranian women during pregnancy is considerably lower than that of most EMRO countries or the one reported by WHO for Iran (> 40%) which had been performed on a small group 16 years ago. The lower prevalence rate of anemia in pregnant women versus the regional rates could be due to the improvements of the national health system and prenatal programs in recent years.

Keywords: Anemia; Hemoglobin; Islamic Republic of Iran; Meta-analysis; Pregnancy; Systematic review.

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Figures

Figure 1
Figure 1
The reported prevalence of anemia in different studies, and the overall estimated prevalence in Iran. The horizontal lines define the reported 95% confidence interval for the prevalence in each study, and the diamond below the graph shows the pooled prevalence.
Figure 2
Figure 2
The average hemoglobin concentration in Iranian pregnant women. The horizontal lines define the reported 95% confidence interval in each study, and the diamond below the graph shows the pooled average.
Figure 3
Figure 3
Mean hemoglobin concentration in pregnancy period. Error bar shows the 95% confidence interval.
See this image and copyright information in PMC

References

    1. Gautam CS, Saha L, Sekhri K, Saha PK. Iron deficiency in pregnancy and the rationality of iron supplements prescribed during pregnancy. Medscape J Med. 2008;10(12):283. - PMC - PubMed
    1. Malee M. Anemia in Pregnancy. Obstet Gynecol. 2008;112(1):201–7. - PubMed
    1. De Benoist B, McLean E, Egli I, Cogswell M. Worldwide prevalence of anaemia 1993–2005, WHO Global Database on Anemia. Geneva: World Health Organization; 2008. p. 21.
    1. Safavi M, Sheykh Aleslam R, Naghavi M, Abdollahi Z, Sadeghian Sharif S, Sadegh Zadeh E, et al. [Prevalence of Iron deficiency anemia among Iranian Pregnant woman, Spring 2001] Iran J Epidemiol. 2006;1(4):1–10. Persian.
    1. Khademi Z, Shahi A, Farshid Far GhR, Zare Sh, Vaziri F. [Prevalence of iron deficiency anemia in pregnant women referred to Shariati hospital in Bandar Abbas, Iran] Hormozgan Med J. 2004;8(1):27–31. Persian.

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