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Comment
. 2013 Aug 8;122(6):856-7.
doi: 10.1182/blood-2013-06-508465.

Defects in DBA: more than meets the eye

Lydie Da Costa  1
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Comment

Defects in DBA: more than meets the eye

Lydie Da Costa. Blood. .
Free article

Abstract

In this issue of Blood, Garçon et al describe successful derivation of induced pluripotent stem cells (iPSs) from fibroblasts of Diamond Blackfan anemia (DBA) patients with 2 distinct ribosomal defects. Using these cells, the authors showed that they not only exhibit defective erythropoiesis but also globally impaired hematopoiesis affecting multipotent progenitors.

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