Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2013 Aug 8;122(6):1091-2.
doi: 10.1182/blood-2013-05-505016.

Lactate dehydrogenase and hemolysis in sickle cell disease

Comment

Lactate dehydrogenase and hemolysis in sickle cell disease

Gregory J Kato et al. Blood. .
No abstract available

PubMed Disclaimer

Figures

Figure 1
Figure 1
Correlation of serum LDH with plasma hemoglobin. Plot of data points derived from Neely and colleagues, with the solid line representing linear regression and the dashed lines indicating 95% confidence interval. Significance was calculated by Pearson correlation analysis of log-transformed data.

Comment on

References

    1. Ballas SK. Lactate dehydrogenase and hemolysis in sickle cell disease. Blood. 2013;121(1):243–244. - PubMed
    1. Kato GJ, McGowan V, Machado RF, et al. Lactate dehydrogenase as a biomarker of hemolysis-associated nitric oxide resistance, priapism, leg ulceration, pulmonary hypertension, and death in patients with sickle cell disease. Blood. 2006;107(6):2279–2285. - PMC - PubMed
    1. Neely CL, Wajima T, Kraus AP, Diggs LW, Barreras L. Lactic acid dehydrogenase activity and plasma hemoglobin elevations in sickle cell disease. Am J Clin Pathol. 1969;52(2):167–169. - PubMed
    1. Engauge Digitizer - Digitizing software. Open source digitizing software. Available at: digitizer.sourceforge.net. Accessed January 10, 2013.
    1. van Beers EJ, Schaap MC, Berckmans RJ, et al. CURAMA study group. Circulating erythrocyte-derived microparticles are associated with coagulation activation in sickle cell disease. Haematologica. 2009;94(11):1513–1519. - PMC - PubMed

Substances